En kvinne i 40-årene med ensidig tåkesyn og smerter ved øyebevegelse

BACKGROUND Toxoplasmosis is a relatively common cause of infectious papillitis and neuroretinitis, which may affect both immunocompetent immunodeficient patients. CASE PRESENTATION A previously healthy woman in her mid-forties presented with subacute onset unilateral blurry vision retrobulbar pain exacerbated by eye movements. Ophthalmological assessment revealed decimal best-corrected visual acuity 0.75, an ipsilateral swollen disc peripapillary infiltrate. Serology indicated acute infection Toxoplasma gondii. Cerebral MRI showed periventricular lesion, oligoclonal bands were detected the cerebrospinal fluid. was positive for IgM IgG against gondii, high IgM/IgG index compatible infection. Toxoplasmosis-related retinitis suspected. The patient responded well to combined systemic intravitreal anti-toxoplasma therapy but developed ocular hypertension. Neither recurrence toxoplasmosis nor clinical symptoms demyelinating disease have been demonstrated during three years follow-up. INTERPRETATION This case illustrates that even when symptoms, fluid findings suggest disease, differential diagnoses must be considered order mitigate negative therapeutic prognostic consequences misdiagnosis.